For decades, testosterone has been a controversial term in women’s health care—a hormone cloaked in the language of virility, often approached with caution rather than curiosity. Historically, its use was narrowly confined to the management of hypoactive sexual desire disorder (HSDD) in postmenopausal women, as defined by the 2019 Global Consensus and the first 2021 clinical guideline of the International Society for the Study of Women’s Sexual Health (ISSWSH). Yet, recent evidence has expanded this horizon, revealing that testosterone’s influence extends well beyond sexuality—into the domains of muscle strength, bone integrity, energy balance, mood, and overall vitality.
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